Advances in genomics have rapidly moved the study of human genomes and microbiomes into the public sphere. With this advancement comes opportunity to engage directly in research and gain access to information relevant to one’s health and well-being, information that participants may also feel compelled to share online. We’ll explore ethics and privacy issues related to the growing field of citizen “-omics” by asking: What are the consequences of the public’s enthusiasm for sharing their personal results online? How do project organizers adequately communicate open-ended risk affiliated with participation in these studies? Are Institutional Review Boards ready for Human Subjects research in the era of social media and online engagement? For journalists writing openly about their participation in these projects, what were the consequences (positive or negative) of sharing one's experience? To what extent will crowd-funding and open-access data policies change the way we think about privacy and ethics?