This discussion will focus on the challenges of tackling a career in science for those with various disabilities, including mobility limitations. Other groups to consider include the deaf community, autistic people, etc. The conversation will also discuss the “invisible glass ceiling” for many scientific professions. Many underserved audiences face similar challenges--including women and ethnic minorities--and we may find lessons and ideas from these groups to apply to the disability community. Let’s talk about ways that the online science community can become a catalyst for more inclusivity of individuals with disabilities in science professions.